Prof.Chen-仿生催化合成研究组

	陈庆安研究员博士生导师（Prof. Dr. Qing-An Chen）电话（Tel）：0411-82463702 邮箱（Mail）：qachen@dicp.ac.cn http://www.researcherid.com/rid/F-7463-2011 本科：中国科学技术大学 2007 博士：中科院大连化学物理研究所 2012 博后：美国加州大学欧文分校 2015 洪堡学者：德国柏林工业大学 2017 B. S. University of Science and Technology of China, 2007 Ph. D. Dalian Institute of Chemical Physics, 2012 Post. Doc. University of California at Irvine, US, 2015 Humboldt Fellow. Technische Universitat Berlin, DE, 2017

陈庆安，福建泉州人。2007年本科毕业于中国科学技术大学化学系，导师尤田耙教授。2012年在中国科学院大连化学物理研究所获得博士学位，导师周永贵研究员。2012年至2015年在美国加州大学欧文分校进行博士后研究，合作导师Vy M.Dong教授。2015年至2017年作为德国洪堡学者在德国柏林工业大学Martin Oestreich教授研究组开展博士后研究工作。2017年加入大连化物所开展独立研究工作，任研究组组长。国家专项人才引进计划青年项目获得者（2017）、大连化物所张大煜青年学者。自开展研究工作以来，先后在Chem. Rev.，Chem. Soc. Rev.，J. Am. Chem. Soc., Angew. Chem. Int. Ed. 等国际权威期刊上发表文章70余篇，总引用次数为3500余次，平均引用50余次（截止2023年9月）。此外还受邀担任J. Am. Chem. Soc.，Chem. Sci.，Chem. Commun. 等国际知名学术期刊的独立审稿人。2017年获得辽宁省自然科学一等奖（排名第二），2020年获得“Thieme Chemistry Journal Award”国际学术奖。目前主要研究领域为仿生催化合成和金属有机化学。

Qing-An Chen was born in 1984 in Fujian Province, China, received a B.S. degree from University of Science and Technology of China in 2007 and earned his Ph.D. from Dalian Institute of Chemical Physics in 2012. He worked with Prof.Vy M. Dong at the University of California Irvine as a postdoctoral fellow from 2012 to 2015. Then he joined Prof. Martin Oestreich's group at Technische Universitat Berlin as an Alexander von Humboldt Fellow. In 2017 he began his independent research career at the Dalian Institute of Chemical Physics, Chinese Academy of Sciences, where currently he is Professor of Chemistry. His research interests include the development of catalytic asymmetric reactions, mechanistic elucidation, and asymmetric synthesis. He has authored over 70 publications, H-index 22.
Representative Publications： 37. Shi-Yu Guo, Yi-Peng Liu, Jin-Song Huang, Li-Bowen He, Gu-Cheng He, Ding-Wei Ji, Boshun Wan, Qing-An Chen.* Visible Light-Induced Chemoselective 1,2-Diheteroarylation of Alkenes. Nature Communications 2024, 15, 6102. 36. Heng Liu, Ding-Wei Ji, Yong-Kang Mei, Yan Liu, Chang-Hui Liu, Xiao-Yu Wang and Qing-An Chen.* Repurposing of Halogenated Organic Pollutants via Alkyl Bromide-Catalyzed Transfer Chlorination. Nature Chemistry 2024, 16, 1505-1514. 35. Bo-Chao Zhou, Bing-Zhi Chen, Ting-Ting Song, Yang Yang, Li-Ming Zhang, Ding-Wei Ji, Boshun Wan, and Qing-An Chen.* Hydrated [3+2] Cyclotelomerization of Butafulvenes to Create Multiple Contiguous Fully Substituted Carbon Centers. Angew. Chem. Int. Ed. 2024, 63, e202317299. 34. Ting-Ting Song, Yong-Kang Mei, Yan Liu, Xiao-Yu Wang, Shi-Yu Guo, Ding-Wei Ji, Boshun Wan, Weiming Yuan,* and Qing-An Chen.* Construction of Bridged Benzazepines via Photo-Induced Dearomatization. Angew. Chem. Int. Ed. 2024, 63, e202314304. 33. Wei-Song Zhang, Ding-Wei Ji, Yang Yang, Ting-Ting Song, Gong Zhang, Xiao-Yu Wang, and Qing-An Chen.* Nucleophilic Aromatization of Monoterpenes from Isoprene under Nickel/Iodine Cascade Catalysis. Nature Communications 2023, 14, 7087. 32. Xiang-Xin Zhang, Hao Zheng, Yong-Kang Mei, Yan Liu, Ying-Ying Liu, Ding-Wei Ji, Boshun Wan, Qing-An Chen.* Photo-Induced Imino Functionalizations of Alkenes via Intermolecular Charge Transfer. Chem. Sci. 2023, 14, 11170-11179. 31.Hao Zheng, Chang-Hui Liu, Xiao-Yu Wang, Yan Liu, Bing-Zhi Chen, Yan-Cheng Hu,and Qing-An Chen. Catalytic Undirected Meta-Selective C–H Borylation of Metallocenes. Adv. Sci. 2023, 2304672. 30. Ying Li, Wei-Song Zhang, Sa-Na Yang, Xiao-Yu Wang, Yan Liu, Ding-Wei Ji,* and Qing-An Chen.* Nickel-Catalyzed Unsymmetrical Bis-Allylation of Alkynes. Angew. Chem. Int. Ed. 2023, 62, e202300036. 29. Wei-Song Zhang, Ding-Wei Ji, Ying Li, Xiang-Xin Zhang, Yong-Kang Mei, Bing-Zhi Chen, Qing-An Chen.* Nickel-catalyzed divergent Mizoroki–Heck reaction of 1,3-dienes. Nature Communications 2023, 14, 651. 28. Ding-Wei Ji, Yan-Cheng Hu, Xiang-Ting Min, Heng Liu, Wei-Song Zhang, Ying Li, Yongjin J. Zhou,and Qing-An Chen.* Skeleton-Reorganizing Coupling Reactions of Cyclohepta-triene and Cycloalkenones with Amines. Angew. Chem. Int. Ed. 2023, 62, e202213074. 27. Gong Zhang, Chao-Yang Zhao, Xiang-Ting Min, Ying Li, Xiang-Xin Zhang, Heng Liu,Ding-Wei Ji, Yan-Cheng Hu, Qing-An Chen.* Nickel-Catalysed Asymmetric Heteroarylative Cyclotelomerization of Isoprene. Nature Catalysis 2022, 5, 708-715. 26. Xiang-Ting Min, Yong-Kang Mei, Bing-Zhi Chen, Li-Bowen He, Ting-Ting Song, Ding-Wei Ji,Yan-Cheng Hu, Boshun Wan, Qing-An Chen.* Rhodium-Catalyzed Deuterated Tsuji-Wilkinson Decarbonylation of Aldehydes with Deuterium Oxide. J. Am. Chem. Soc. 2022, 144, 11081-11087. 25. Chao-Yang Zhao, Ying-Ying Liu, Xiang-Xin Zhang, Gu-Cheng He, Heng Liu, Ding-Wei Ji,Yan-Cheng Hu, Qing-An Chen.* Bioinspired and Ligand-Regulated Unnatural Prenylation and Geranylation of Oxindoles with Isoprene under Pd Catalysis. Angew. Chem. Int. Ed. 2022, 61, e202207202. 24. Xin Huang,^† Bing-Zhi Chen,^† Pengbin Li, Ding-Wei Ji, Jinxian Liu, Hao Zheng, Sa-Na Yang, Yan-Cheng Hu, Boshun Wan, Xiang-Ping Hu, Chunling Fu, Yankai Huang, Jian Zheng,* Qing-An Chen,* Shengming Ma.* Palladium-catalyzed construction of butafulvenes. Nature Chemistry 2022, 14, 1185-1192. 23. Hao Zheng, Chang-Hui Liu, Shi-Yu Guo, Gu-Cheng He, Xiang-Ting Min, Bo-Chao Zhou, Ding-Wei Ji, Yan-Cheng Hu, Qing-An Chen.* Regioselective C−H Phosphorylation of Group 8 Metallocenes under Electrochemical Autocatalysis. Nature Communications 2022, 13, 3496. 22. Yan-Cheng Hu, Xiang-Ting Min, Ding-Wei Ji, Qing-An Chen.* Catalytic Prenylation and Reverse-Prenylation of Aromatics. Trends in Chemistry 2022, 4, 658-675. 21. Gu-Cheng He,^† Shi-Yu Guo,^† Hao Zheng, Chang-Hui Liu, Ying Li, Xiang-Ting Min, Ding-Wei Ji and Qing-An Chen.* Photo-Induced Catalytic C−H Heteroarylation of Group 8 Metallocenes. Cell Rep. Phys. Sci. 2022, 3, 100768. 20. Wei-Song Zhang, Ding-Wei Ji, Ying Li, Xiang-Xin Zhang, Chao-Yang Zhao, Yan-Cheng Hu and Qing-An Chen.* Regio- and Stereoselective Diarylation of 1,3-Dienes via Ni/Cr Co-catalysis. ACS Catal. 2022, 12, 2158-2165. 19. Shi-Yu Guo, Fan Yang, Ting-Ting Song, Yu-Qing Guan, Xiang-Ting Min, Ding-Wei Ji, Yan-Cheng Hu and Qing-An Chen.* Photo-Induced Catalytic Halopyridylation of Alkenes. Nature Communications 2021, 12, 6538. 18. Heng Liu, Gu-Cheng He, Chao-Yang Zhao, Xiang-Xin Zhang, Ding-Wei Ji, Yan-Cheng Hu and Qing-An Chen.* Redoxdivergent Construction of (Dihydro)thiophenes with DMSO. Angew. Chem. Int. Ed. 2021, 60, 24284-24291. 17. Chao-Yang Zhao, Ding-Wei Ji, Hao Zheng, Gu-Cheng He, Heng Liu, Yan-Cheng Hu, and Qing-An Chen.* Pd-Catalyzed Redox Divergent Coupling of Ketones with Terpenols. ACS Cat. 2021,11, 6825-6834. 16. Wen-Shuang Jiang⁺, Ding-Wei Ji⁺, Wei-Song Zhang, Gong Zhang, Xiang-Ting Min, Yan-Cheng Hu, Xu-Liang Jiang, and Qing-An Chen. Orthogonal Regulation of Nucleophilic and Electrophilic Sites in Pd-Catalyzed Regiodivergent Couplings between Indazoles and Isoprene. Angew. Chem. Int. Ed. 2021, 60, 8321-8328. 15. Yan-Cheng Hu⁺, Yingying Zhao⁺, Boshun Wan, Qing-An Chen. Reactivity of Ynamides in Catalytic Intermolecular Annulations. Chem. Soc. Rev. 2021, 50, 2582-2625. 14. Xiang-Ting Min, Ding-Wei Ji, Yu-Qing Guan, Shi-Yu Guo, Yan-Cheng Hu, Boshun Wan, Qing-An Chen* Visible Light-Induced Bifunctional Rhodium Catalysis for Decarbonylative Coupling of Imides with Alkynes. Angew. Chem. Int. Ed. 2021, 60, 1583-1587. 13. Chang-Sheng Kuai⁺, Ding-Wei Ji⁺, Chao-Yang Zhao, Heng Liu, Yan-Cheng Hu, Qing-An Chen.* Ligand Regulated Regiodivergent Hydrosilylation of Isoprene under Iron Catalysis. Angew. Chem. Int. Ed. 2020, 59, 19115-19120. 12. Chao-Yang Zhao, Hao Zheng, Ding-Wei Ji, Xiang-Ting Min, Yan-Cheng Hu, and Qing-An Chen.* Copper-Catalyzed Asymmetric Carboboronation of Allenes to Access α-Quaternary Amino Esters with Adjacent Stereocenters. Cell Rep. Phys. Sci. 2020, 1, 100067. 11. Jun Yang, Ding-Wei Ji, Yan-Cheng Hu, Xiang-Ting Min, Xiang-Ge Zhou,* Qing-An Chen.* Cobalt-Catalyzed Hydroxymethylarylation of Terpenes with Formaldehyde and Arenes. Chem. Sci. 2019, 10, 9560-9564. 10. Ding-Wei Ji, Yan-Cheng Hu, Hao Zheng, Chao-Yang Zhao, Qing-An Chen.* and Vy M. Dong. Catalytic Regioselectivity Switch in Pd-Catalyzed Hydroallylation of Alkynes. Chem. Sci. 2019, 10, 6311-6315. 9. Yan-Cheng Hu, Ding-Wei Ji, Chao-Yang Zhao, Hao Zheng, Qing-An Chen.* Catalytic Prenylation and Reverse-Prenylation of Indoles with Isoprene: Regioselectivity Manipulation by Metal-Hydride. Angew. Chem. Int. Ed. 2019, 58, 5438-5442. 8. Qing-An Chen, Hendrik F. T. Klare, and Martin Oestreich.* Bronsted Acid-Promoted Formation of Stabilized Silylium Ions for Catalytic Friedel-Crafts C-H Silylation. J. Am. Chem. Soc. 2016, 138, 7868-7871. 7. Qing-An Chen, Zhiwei Chen, Vy M. Dong.* Rhodium-Catalyzed Enantioselective Hydroamination of Alkynes with Indolines. J. Am. Chem. Soc. 2015, 137, 8392-8395. 6. Qing-An Chen, Faben A. Cruz, Vy M. Dong.* Alkyne Hydroacylation: Switching Regioselectivity by Tandem Ruthenium Catalysis. J. Am. Chem. Soc. 2015, 137, 3157-3160. 5. Qing-An Chen, Daniel K. Kim, Vy M. Dong.* Regioselective Hydroacylation of 1,3-Dienes by Cobalt-Catalysis. J. Am. Chem. Soc. 2014, 136, 3772-3775. 4. Qing-An Chen, Zhi-Shi Ye, Ying Duan and Yong-Gui Zhou.* Homogeneous Palladium Catalyzed Asymmetric Hydrogenation. Chem. Soc. Rev. 2013, 42, 497-511. 3. Qing-An Chen, Kai Gao, Ying Duan, Zhi-Shi Ye, Lei Shi, Yan Yang and Yong-Gui Zhou.* Dihydrophenanthridine: A New and Easily Regenerable NAD(P)H Model for Biomimetic Asymmetric Hydrogenation. J. Am. Chem. Soc. 2012, 134, 2442-2448. 2. Qing-An Chen, Mu-Wang Chen, Chang-Bin Yu, Lei Shi, Duo-Sheng Wang, Yan Yang and Yong-Gui Zhou.* Biomimetic Asymmetric Hydrogenation: In Situ Regenerable Hantzsch Esters for Asymmetric Hydrogenation of Benzoxazinones. J. Am. Chem. Soc. 2011, 133, 16432-16435. 1. Qing-An Chen, Duo-Sheng Wang, Yong-Gui Zhou,* Ying Duan, Hong-Jun Fan,* Yan Yang, Zhang Zhang. Convergent Asymmetric Disproportionation Reactions: Metal/Bronsted Acid Relay Catalysis for Enantioselective Reduction of Quinoxalines. J. Am. Chem. Soc. 2011, 133, 6126-6129.